Specialized smart soft contact lenses can address global issue of glaucoma diagnosis, management

The vision of Purdue University biomedical engineer Chi Hwan Lee to develop specialized smart soft contact lenses that can accurately measure intraocular pressure (IOP) in a person’s eye could be the latest answer to stopping glaucoma-related blindness. Lee, the Leslie A. Geddes Associate Professor of Biomedical Engineering in Purdue’s Weldon School of Biomedical Engineering, led […]

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Study finds the mechanism used by metastatic cancer cells to infiltrate the liver

Metastasis—when cancer spreads to form new tumors—causes approximately 90% of cancer-related deaths. Because metastatic cancer cells circulate in the blood, the liver—which filters the blood—is considered the most vulnerable organ, so treatments that prevent liver metastasis are urgently needed. A team of Osaka Metropolitan University researchers discovered a mechanism that allows metastatic cancer cells to […]

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SGLT2 inhibitors and GLP1 receptor antagonists improve type-2 diabetes outcomes, but are not cost effective

A cost-effectiveness study of sodium–glucose cotransporter-2 (SGLT2) inhibitors and glucagon-like peptide-1 (GLP1) receptor agonists has found that the use of these medications as first-line treatment for type-2 diabetes would improve outcomes, but their costs would need to decrease by at least 70 percent to be cost-effective. Type-2 diabetes affects more than 30 million Americans and […]

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Disruption of MTSS2 function causes a new syndromic intellectual disability

An Undiagnosed Diseases Network (UDN) study led by Dr. Hugo Bellen, investigator at the Jan and Dan Duncan Neurological Research Institute (NRI) at Texas Children’s Hospital and distinguished service professor at the Baylor College of Medicine, has found a spontaneous mutation in MTSS2 gene to be the underlying cause of a new syndromic intellectual disability. […]

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